|
Gross, Harald; Stockwell, Virginia O.; Henkels, Marcella D.; Nowak-Thompson, Brian; Loper, Joyce E.; Gerwick, William H.. The Genomisotopic Approach: A Systematic Method to Isolate Products of Orphan Biosynthetic Gene Clusters. Chemistry & Biology (2007), 14(1), 53-63. Andersson, Mats X.; Hamberg, Mats; Kourtchenko, Olga; Brunnstroem, Aasa; McPhail, Kerry L.; Gerwick, William H.; Goebel, Cornelia; Feussner, Ivo; Ellerstroem, Mats. Oxylipin Profiling of the Hypersensitive Response in Arabidopsis thaliana. Formation of a Novel Oxo-Phytodienoic Acid-Containing Galactolipid, Arabidopside E. Journal of Biological Chemistry (2006), 281(42), 31528-31537. Suyama, Takashi L.; Gerwick, William H. Practical Total Syntheses of Epiquinamide Enantiomers. Organic Letters (2006), 8(20), 4541-4543. Gu, Liangcai; Jia, Junyong; Liu, Haichuan; Hkansson, Kristina; Gerwick, William H.; Sherman, David H. Metabolic Coupling of Dehydration and Decarboxylation in the Curacin A Pathway: Functional Identification of a Mechanistically Diverse Enzyme Pair. Journal of the American Chemical Society (2006), 128(28), 9014-9015. Flatt, Patricia M.; O'Connell, Susan J.; McPhail, Kerry L.; Zeller, Gloria; Willis, Christine L.; Sherman, David H.; Gerwick, William H. Characterization of the Initial Enzymatic Steps of Barbamide Biosynthesis. Journal of Natural Products (2006), 69(6), 938-944. Ramaswamy, Aishwarya V.; Flatt, Patricia M.; Edwards, Daniel J.; Simmons, T. Luke; Han, Bingnan; Gerwick, William H. The secondary metabolites and biosynthetic gene clusters of marine cyanobacteria. Applications in biotechnology. Frontiers in Marine Biotechnology (2006), 175-224. Torres-Mendoza, Daniel; Gonzalez, Jose; Ortega-Barria, Eduardo; Heller, Maria V.; Capson, Todd L.; McPhail, Kerry; Gerwick, William H.; Cubilla-Rios, Luis. Weakly Antimalarial Flavonol Arabinofuranosides from Calycolpus warscewiczianus. Journal of Natural Products (2006), 69(5), 826-828. Simmons, T. Luke; McPhail, Kerry L.; Ortega-Barria, Eduardo; Mooberry, Susan L.; Gerwick, William H.. Belamide A, a new antimitotic tetrapeptide from a Panamanian marine cyanobacterium. Tetrahedron Letters (2006), 47(20), 3387-3390. Correa, Jhonny Edmith; Rios, Carlos Hernan; Castillo, Amparo del Rosario; Romero, Luz I.; Ortega-Barria, Eduardo; Coley, Phyllis D.; Kursar, Thomas A.; Heller, Maria Veronica; Gerwick, William H.; Rios, Luis Cubilla. Minor alkaloids from Guatteria dumetorum with antileishmanial activity. Planta Medica (2006), 72(3), 270-272. Gross, Harald; Goeger, Douglas E.; Hills, Patrice; Mooberry, Susan L.; Ballantine, David L.; Murray, Thomas F.; Valeriote, Frederick A.; Gerwick, William H. Lophocladines, Bioactive Alkaloids from the Red Alga Lophocladia sp. Journal of Natural Products (2006), 69(4), 640-644. Andrianasolo, Eric H.; France, Dennis; Cornell-Kennon, Susan; Gerwick, William H. DNA Methyl Transferase Inhibiting Halogenated Monoterpenes from the Madagascar Red Marine Alga Portieria hornemannii. Journal of Natural Products (2006), 69(4), 576-579. Han, Bingnan; Gross, Harald; Goeger, Douglas E.; Mooberry, Susan L.; Gerwick, William H. Aurilides B and C, cancer cell toxins from a Papua New Guinea collection of the marine cyanobacterium Lyngbya majuscula. Journal of Natural Products (2006), 69(4), 572-575. Dorrestein, Pieter C.; Blackhall, Jonathan; Straight, Paul D.; Fischbach, Michael A.; Garneau-Tsodikova, Sylvie; Edwards, Daniel J.; McLaughlin, Shaun; Lin, Myat; Gerwick, William H.; Kolter, Roberto; Walsh, Christopher T.; Kelleher, Neil L. Activity Screening of Carrier Domains within Nonribosomal Peptide Synthetases Using Complex Substrate Mixtures and Large Molecule Mass Spectrometry. Biochemistry (2006), 45(6), 1537-1546. |
|
LePage, Keith T.; Dickey, Robert W.; Gerwick, William H.; Jester, Edward L.; Murray, Thomas F. On the use of neuro-2a neuroblastoma cells versus intact neurons in primary culture for neurotoxicity studies. Critical Reviews in Neurobiology (2005), 17(1), 27-50. Han, Bingnan; McPhail, Kerry L.; Gross, Harald; Goeger, Douglas E.; Mooberry, Susan L.; Gerwick, William H. Isolation and structure of five lyngbyabellin derivatives from a Papua New Guinea collection of the marine cyanobacterium Lyngbya majuscula. Tetrahedron (2005), 61(49), 11723-11729. LePage, K. T.; Goeger, D.; Yokokawa, F.; Asano, T.; Shioiri, T.; Gerwick, W. H.; Murray, T. F. The neurotoxic lipopeptide kalkitoxin interacts with voltage-sensitive sodium channels in cerebellar granule neurons. Toxicology Letters (2005), 158(2), 133-139. Flatt, Patricia M.; Gautschi, Jeffrey T.; Thacker, Robert W.; Musafija-Girt, Mirjam; Crews, Phillip; Gerwick, William H. Identification of the cellular site of polychlorinated peptide biosynthesis in the marine sponge Dysidea (Lamellodysidea) herbacea and symbiotic cyanobacterium Oscillatoria spongeliae by CARD-FISH analysis. Marine Biology (Heidelberg, Germany) (2005), 147(3), 761-774. Sabry, Omar M. M.; Andrews, Simeon; McPhail, Kerry L.; Goeger, Douglas E.; Yokochi, Alexandre; LePage, Keith T.; Murray, Thomas F.; Gerwick, William H.. Neurotoxic Meroditerpenoids from the Tropical Marine Brown Alga Stypopodium flabelliforme. Journal of Natural Products (2005), 68(7), 1022-1030. Han, Bingnan; Goeger, Doug; Maier, Claudia S.; Gerwick, William H.. The wewakpeptins, cyclic depsipeptides from a Papua New Guinea collection of the marine cyanobacterium Lyngbya semiplena. Journal of Organic Chemistry (2005), 70(8), 3133-3139. Andrianasolo, Eric H.; Gross, Harald; Goeger, Douglas; Musafija-Girt, Mirjam; McPhail, Kerry; Leal, Rachel M.; Mooberry, Susan L.; Gerwick, William H.. Isolation of Swinholide A and Related Glycosylated Derivatives from Two Field Collections of Marine Cyanobacteria. Organic Letters (2005), 7(7), 1375-1378. Simmons, T. Luke; Andrianasolo, Eric; McPhail, Kerry; Flatt, Patricia; Gerwick, William H.. Marine natural products as anticancer drugs. Molecular Cancer Therapeutics (2005), 4(2), 333-342. |
|
Edwards, Daniel J.; Gerwick, William H.. Lyngbyatoxin Biosynthesis: Sequence of Biosynthetic Gene Cluster and Identification of a Novel Aromatic Prenyltransferase. Journal of the American Chemical Society (2004), 126(37), 11432-11433. Chang, Zunxue; Sitachitta, Namthip; Rossi, James V.; Roberts, Mary Ann; Flatt, Patricia M.; Jia, Junyong; Sherman, David H.; Gerwick, William H.. Biosynthetic Pathway and Gene Cluster Analysis of Curacin A, an Antitubulin Natural Product from the Tropical Marine Cyanobacterium Lyngbya majuscula. Journal of Natural Products (2004), 67(8), 1356-1367. Williamson, R. Thomas; Singh, Inder Pal; Gerwick, William H.. Taveuniamides: new chlorinated toxins from a mixed assemblage of marine cyanobacteria. Tetrahedron (2004), 60(33), 7025-7033. Yokokawa, Fumiaki; Asano, Toshinobu; Okino, Tatsufumi; Gerwick, William H.; Shioiri, Takayuki. An expeditious total synthesis of kalkitoxins: determination of the absolute stereostructure of natural kalkitoxin. Tetrahedron (2004), 60(32), 6859-6880. Edwards, Daniel J.; Marquez, Brian L.; Nogle, Lisa M.; McPhail, Kerry; Goeger, Douglas E.; Roberts, Mary Ann; Gerwick, William H.. Structure and Biosynthesis of the Jamaicamides, New Mixed Polyketide-Peptide Neurotoxins from the Marine Cyanobacterium Lyngbya majuscula. Chemistry & Biology (2004), 11(6), 817-833. McPhail, Kerry L.; France, Dennis; Cornell-Kennon, Susan; Gerwick, William H.. Peyssonenynes A and B, novel enediyne oxylipins with DNA methyl transferase inhibitory activity from the red marine alga Peyssonnelia caulifera. Journal of Natural Products (2004), 67(6), 1010-1013. Takamatsu, Satoshi; Nagle, Dale G.; Gerwick, William H.. Secondary metabolites from marine cyanobacteria and algae inhibit LFA-1/ICAM-1 mediated cell adhesion. Planta Medica (2004), 70(2), 127-131. Li, W. I.; Marquez, B. L.; Okino, T.; Yokokawa, F.; Shioiri, T.; Gerwick, W. H.; Murray, T. F. Characterization of the Preferred Stereochemistry for the Neuropharmacologic Actions of Antillatoxin. Journal of Natural Products (2004), 67(4), 559-568. Gafner, Stefan; Bergeron, Chantal; McCollom, Megan M.; Cooper, Lorena M.; McPhail, Kerry L.; Gerwick, William H.; Angerhofer, Cindy K. Evaluation of the Efficiency of Three Different Solvent Systems to Extract Triterpene Saponins from Roots of Panax quinquefolius Using High-Performance Liquid Chromatography. Journal of Agricultural and Food Chemistry (2004), 52(6), 1546-1550. Crews, Phillip; Gerwick, William; Schmitz, Francis; France, Dennis; Bair, Kenneth; Wright, Amy; Hallock, Yali. Molecular Approaches to Discover Marine Natural Product Anticancer Leads - An Update from a Drug Discovery Group Collaboration. Pharmaceutical Biology (Lisse, Netherlands) (2003), 41(Suppl. 1), 39-52. Han, Bingnan; McPhail, Kerry L.; Ligresti, Alessia; Di Marzo, Vincenzo; Gerwick, William H.. Semiplenamides A-G, fatty acid amides from a Papua New Guinea collection of the marine cyanobacterium Lyngbya semiplena. Journal of Natural Products (2003), 66(10), 1364-1368. Tan, Lik Tong; Sitachitta, Namthip; Gerwick, William H.. The guineamides, novel cyclic depsipeptides from a Papua New Guinea collection of the marine cyanobacterium Lyngbya majuscula. Journal of Natural Products (2003), 66(6), 764-771. Takamatsu, Satoshi; Hodges, Tyler W.; Rajbhandari, Ira; Gerwick, William H.; Hamann, Mark T.; Nagle, Dale G. Marine Natural Products as Novel Antioxidant Prototypes. Journal of Natural Products (2003), 66(5), 605-608. Nogle, Lisa M.; Gerwick, William H.. Diverse secondary metabolites from a Puerto Rican collection of Lyngbya majuscula. Journal of Natural Products (2003), 66(2), 217-220. Gerwick, William H.; Leslie, Pauline; Long, G. Cliona; Marquez, Brian L.; Willis, Christine L. [6-13C]-(2S,4S)-5-Chloroleucine: synthesis and incubation studies with cultures of the cyanobacterium, Lyngbya majuscula. Tetrahedron Letters (2002), Volume Date 2003, 44(2), 285-288. Nogle, Lisa M.; Marquez, Brian L.; Gerwick, William H.. Wewakazole, a novel cyclic dodecapeptide from a Papua New Guinea Lyngbya majuscula. Organic Letters (2003), 5(1), 3-6. McPhail, Kerry L.; Gerwick, William H.. Three new malyngamides from a Papua New Guinea collection of the marine cyanobacterium Lyngbya majuscula. Journal of Natural Products (2003), 66(1), 132-135. Stevenson, Christopher S.; Capper, Elizabeth A.; Roshak, Amy K.; Marquez, Brian; Eichman, Chris; Jackson, Jeffrey R.; Mattern, Michael; Gerwick, William H.; Jacobs, Robert S.; Marshall, Lisa A. The identification and characterization of the marine natural product scytonemin as a novel antiproliferative pharmacophore. Journal of Pharmacology and Experimental Therapeutics (2002), 303(2), 858-866. Williamson, R. Thomas; Boulanger, Anna; Vulpanovici, Alexandra; Roberts, Mary A.; Gerwick, William H.. Structure and absolute stereochemistry of phormidolide, a new toxic metabolite from the marine cyanobacterium Phormidium sp. Journal of Organic Chemistry (2002), 67(23), 7927-7936. Chang, Zunxue; Flatt, Patricia; Gerwick, William H.; Nguyen, Viet-Anh; Willis, Christine L.; Sherman, David H. The barbamide biosynthetic gene cluster: a novel marine cyanobacterial system of mixed polyketide synthase (PKS)-non-ribosomal peptide synthetase (NRPS) origin involving an unusual trichloroleucyl starter unit. Gene (2002), 296(1-2), 235-247. Zheng, Wei; Wise, Mitchell L.; Wyrick, Annette; Metz, James G.; Yuan, Ling; Gerwick, William H.. Polyenoic fatty acid isomerase from the marine alga Ptilota filicina: protein characterization and functional expression of the cloned cDNA. Archives of Biochemistry and Biophysics (2002), 401(1), 11-20. Marquez, Brian L.; Watts, Karl Shawn; Yokochi, Alexandre; Roberts, Mary Ann; Verdier-Pinard, Pascal; Jimenez, Jorge I.; Hamel, Ernest; Scheuer, Paul J.; Gerwick, William H.. Structure and absolute stereochemistry of hectochlorin, a potent stimulator of actin assembly. Journal of Natural Products (2002), 65(6), 866-871. Gerwick, William H.; Singh, Inder Pal. Structural diversity of marine oxylipins. Lipid Biotechnology (2002), 249-275. Tan, Lik Tong; Marquez, Brian L.; Gerwick, William H.. Lyngbouilloside, a novel glycosidic macrolide from the marine cyanobacterium Lyngbya bouillonii. Journal of Natural Products (2002), 65(6), 925-928. Gerwick, William. The Phytochemistry of the Macro and Blue-Green Algae of the Arabian Gulf. Journal of Natural Products (2002), 65(6), 950-951. Stevenson, C. S.; Capper, E. A.; Roshak, A. K.; Marquez, B.; Grace, K.; Gerwick, W. H.; Jacobs, R. S.; Marshall, L. A. Scytonemin - a marine natural product inhibitor of kinases key in hyperproliferative inflammatory diseases. Inflammation Research (2002), 51(2), 112-114. Nogle, Lisa M.; Gerwick, William H.. Somocystinamide A, a novel cytotoxic disulfide dimer from a Fijian marine cyanobacterial mixed assemblage. Organic Letters (2002), 4(7), 1095-1098. Nogle, Lisa M.; Gerwick, William H.. Isolation of four new cyclic depsipeptides, antanapeptins A-D, and dolastatin 16 from a Madagascan collection of Lyngbya majuscula. Journal of Natural Products (2002), 65(1), 21-24. Yoo, Hye-Dong; Ketchum, Sharon O.; France, Dennis; Bair, Ken; Gerwick, William H.. Vidalenolone, a Novel Phenolic Metabolite from the Tropical Red Alga Vidalia sp. Journal of Natural Products (2002), 65(1), 51-53. |